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Unlike somatic cells, which possess a variety of DNA repair pathways to correct oxidative damage, spermatozoa have only one active DNA repair enzyme, 8-oxoguanine DNA glycosylase (OGG1), which is responsible for repairing oxidative base lesions ( 3.3 Protein oxidation Protein oxidation represents another key mechanism by which oxidative stress impairs sperm function

Patients who use their semaglutide treatment window (typically 1836 months) to rebuild exercise capacity, retrain eating behaviors, and stabilize blood sugar achieve the best outcomes when transitioning off medication

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Prog Neuropsychopharmacol Biol Psychiatry 20:11591170 Holmay MJ, Terpstra M, Coles LD, Mishra U, Ahlskog M, Oz G, Cloyd JC, Tuite PJ (2013) N-Acetylcysteine boosts brain and blood glutathione in Gaucher and Parkinson diseases