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Key Takeaways Fatigue is a common side effect of tirzepatide, especially during the first few weeks or after a dose increase, as the body adjusts to the medication

Side effects can occur with any medication

Conclusion: Managing Cold Sensations on Mounjaro Feeling cold while on Mounjaro is usually a temporary part of your body adapting to weight loss and metabolic changes

Recurring themes included food-noise relief, appetite and weight expectations, GI complaints, fatigue and temperature complaints, access barriers, plateaus, return of hunger, and non-response after switching from another GLP-1-related medication