UBE1L Polyclonal Antibody, 50ul Drying & Desiccation Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different isoforms have been described for this gene

This caspase is able to cleave and activate its own precursor protein

In addition| this protein interacts with and phosphorylates BRCA1| allowing BRCA1 to restore survival after DNA damage

|PTM:During G0 and early G1 phase of the cell cycle| phosphorylated on Ser-639 and on 5 sites within the domain B

UBE1L Polyclonal Antibody, 50ul Drying & Desiccation Several alternatively spliced transcript variantsThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin activating enzyme family. The encoded enzyme is a retinoid target that triggers