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The lipolytic stimulus is characterized by the reduction of fat cells through inhibition of the adenosine or phosphodiesterase receptor, activation of the beta adrenergic receptor or inhibition of the alpha 2 receptor

MACE, major adverse cardiovascular event

Under metabolic stress, MOTS-c translocates from the cytoplasm to the nucleus, directly regulating gene expression related to stress adaptation

compositions according to the invention exert favorable effects at the level of hydrocarbon or electrolytic nitrogen metabolism of various tissues, and, consequently, at the level of the functions of these in different physiological or pathological situations, in particular when these are accompanied by disturbances of muscle functions (hypoexcitability, hypocontractility)