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LaMoia 2021)

During the immune exhaustion characteristic of chronic infection, an increase in CTLA-4 expression is observed, which may increase IDO activation (234)

Alternative Transfer Method If preferred, the contents of the BSS PLUS Part II component may be aspirated with an 18-gauge cannula attached to a 20 mL syringe and then transferred into the Part I bag

In contrast, desensitization may be defined as a reduction of signal transduction from OR after acute activation by agonists that recovers when cells or tissues are placed in agonist-free medium