Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis May also reduce the inherent

May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites)

Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107

ATBF1 and MECP2 (By similarity)

The gene is ubiquitously expressed but is found in abundance in the spleen

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 20ul DNA Oligo Synthesis May also reduce the inherentMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.