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CO8G Polyclonal Antibody, 50ul Bacterial Expression This gene product is a

SKU: 55839236004

4.1
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CO8G Polyclonal Antibody, 50ul Bacterial Expression This gene product is aThe protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide linked C8 alpha gamma heterodimer and a non covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement mediated bacterial killing, the gamma

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Description

This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain

It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele

CO8G Polyclonal Antibody, 50ul Bacterial Expression This gene product is aThe protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide linked C8 alpha gamma heterodimer and a non covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement mediated bacterial killing, the gamma

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