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Methods Study cohort (SURMOUNT-1 clinical trial) Ethical approval and study populations The study was conducted in accordance with the principles of the Declaration of Helsinki, Good Clinical Practice guidelines and all applicable regulatory requirements Study protocol and informed consent documents were approved by independent ethics committees and institutional review boards at all participating trial sites

Injection-site reactions and hypersensitivity-related events were also rare and mild, all resolving spontaneously

Mistake 2: ignoring vial concentration changes Your pharmacy switches from 10 mg/mL to 20 mg/mL