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Raltitrexed - CAS# 112887-68-0 sinone Naringin suppresses NF-κB signaling pathway

Raltitrexed - CAS# 112887-68-0 sinone Naringin suppresses NF-κB signaling pathway

Name: Raltitrexed - CAS# 112887-68-0 sinone Naringin suppresses NF-κB signaling pathway
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Raltitrexed - CAS# 112887-68-0 sinone Naringin suppresses NF-κB signaling pathwayRaltitrexed, also known as ZD 1694, is an antimetabolite drug used in treatment of colorectal cancer since 1998. It may also be used in the treatment of malignant mesothelioma. It is an inhibitor of thymidylate synthase, and is manufactured by AstraZeneca. Raltitrexed is a quinazoline folate analogue with antineoplastic activity. After transport into cells via the reduced folate carrier, raltitrexed undergoes intracellular polyglutamation and blocks

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Description

Naringin suppresses NF-κB signaling pathway

and genetic analysis

CAS Number: 1351758-81-0

which is essential for inflammatory cytokine-induced activation of nuclear factor kappaB (NF-kappaB)

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