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Epithalon 6

Guest Information: Alex DiFeliceantonio, Ph.D., appetitive neuroscientist, assistant professor, Fralin Biomedical Research Institute at Virginia Tech University

Expensive APIs: When maximizing drug encapsulation efficiency is crucial to reduce waste of high-cost payloads like mRNA or rare peptides

ML226 treatment resulted in HIF-1 stabilization, upregulation of HIF-1 target genes ( CAIX and VEGF ), and activation of a HIF-1 fluorescent reporter (HRE-GFP ODD ) in HeLa cells, similar to treatment with cell-permeable (DM-2OG