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So I think when you look at master, master, so we know what drives, so, over the last 20 years we now know the genomics of aging and Peter Attia gets into that in detail in his good book, in his longevity book, and get into the pathways that are fundamental, right

Embodiment 3 [0053] Expression and purification of embodiment 3 fusion protein [0054] Transfer the seed liquid of the recombinant positive engineering strain of Example 2 to LB medium according to the inoculum size of 2%, cultivate it at 37C until OD600=0.6, add 50 l of 0.5mol / L IPTG, induce at 15C for 16 hours, and collect by centrifugation For each 1 g of wet bacteria, resuspend in 10 mL of lysis buffer (50 mM Tris-HCl, 50 mM NaCl, 5% glycerol, pH 8.0, 17 l (10 mg / mL PMSF)), ultrasonicate and centrifuge to obtain supernatant and precipitate

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Un total de 307 participantes fueron aleatorizados en proporcin 2:1: 205 al grupo de SEMA oral y 102 al grupo de placebo