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In contrast, IGFBP 5 induces cellular adhesion and inhibits migration of MCF7 cells via the activation of AKT in an IGF-independent manner, consistent with previous studies suggesting an apoptotic role for IGFBP 5 in BrCa [68]

Laprairie, University of Saskatchewan, Canada Franjo Grotenhermen, Nova Institut GmbH, Germany Updates Copyright 2022 Souza, Fassoni-Ribeiro, Batista, Ushirohira, Zuardi, Guimares, Campos, Osrio, Elias, Souza, Fassoni, Hallak and Crippa