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Execellent summary, El-Refaey and an important milestone for the oral GLP-1 space

This will open up its use beyond diabetes management and more people will be able to benefit from its weight loss property

Interestingly, higher incidence of diabetic retinopathy (DR) complications was noted in patients taking semaglutide (3.0%) compared to placebo (1.5%) in clinical trials, with greater risk in those with a history of DR [32]

Cell Metab (2005) 1:15968.10.1016/j.cmet.2005.02.003 60 RichardsPParkerHEAdriaenssensAEHodgsonJMCorkSCTrappSet alIdentification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model