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In conclusion, oral semaglutide was superior to placebo in reducing HbA 1c (3 mg, 7 mg and 14 mg) and body weight (7 mg and 14 mg) after 26 weeks of treatment in a predominantly Chinese population with type 2 diabetes treated with diet and exercise only (trial product estimand)

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For patients with significant insulin resistance, this baseline helps track one of the key metabolic improvements that GLP-1 medications produce