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Following release, both GLP-1 and PYY undergo enzymatic cleavage in the intestinal endothelium and liver by dipeptidyl peptidase IV (DPPIV), which converts GLP-1 to an inactive form, and truncates PYY 136 to its Y2 selective form, PYY 336

Epithalon works best when understood as one tool within a broader strategy that includes hormonal optimization, metabolic support, lifestyle factors, and targeted supplementation

The potential impact of TGPL on HT could be linked to enhanced intestinal flora diversity and reduced mucosal barrier damage, although direct connections between microbiota composition and thyroid autoimmunity require further investigation (Mu et al

Results from laboratory research should not be interpreted as evidence of effects in humans without appropriate clinical evidence