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El aumento de las tasas de mortalidad por ascitis en la quinta semana y hacia el final del ensayo puede atribuirse al aumento de la demanda de oxgeno debido al aumento del peso vivo de los animales y a la incapacidad de satisfacerlos adecuadamente, as como al uso de alimento en forma de grnulos

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NT-proBNP = N-terminal pro b-type natriuretic peptide, HF = Heart failure, ECG = electrocardiogram, eGFR = estimated glomerular filtration rate, BMI = body mass index, SBP = systolic blood pressure, T2DM = type 2 diabetes mellitus