CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification The encoded protein possesses an

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal| followed by two fibronectin type-III motifs

It is thought to be involved in the process of myelination

Mutations in this gene cause glycogen storage disease type 14

Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells

CD43 Rabbit Polyclonal Antibody, 50ul Peptide Modification The encoded protein possesses anThe protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes T lymphocytes monocytes granulocytes and some B lymphocytes. It may be part of a physiologic ligand receptor complex involved in T cell activation. During T cell activation this protein is actively removed from the T cell APC (antigen presenting cell) contact site suggesting a negative regulatory role in adaptive immune response.