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MTs and PCs are two forms of peptide metal-binding ligands that are essential for the detoxification and tolerance of HMs in plants that are subjected to HM stress ( PCs are synthesized from GSH and are induced by a variety of HMs, including Cd, Hg, Ag, Cu, Ni, Au, Pb, As, and Zn ( 2+ within the cytosol, and they complex Cd ions through the thiolic group (SH) of cysteine (Salbitani et al., 2023)