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GBA-JGKX-2507, China),Traditional Chinese Medicine Research Fund of Guangdong Provincial Bureau (202405061017183700, China), the Natural Science Foundation of Guangdong Province(2023A1515010720, China), Science and Technology Project of Guangzhou City (2023A04J1827, China)

Human studies indicate that the insulinotropic action of GIP is blunted in individuals with severe hyperglycemia, in contrast to the intact action of GLP-1

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