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TOK-1 Polyclonal Antibody, 20ul Mammalian Expression This protein acts as a

SKU: 77205703018

4.9
DKK97.20 DKK131.20

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TOK-1 Polyclonal Antibody, 20ul Mammalian Expression This protein acts as aBCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N terminal half shares moderate homology with regions of calmodulin and M calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a

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Description

This protein acts as a sequence-specific repressor of transcription

and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers

serves as the scaffold for assembly of the remainder of the transcription complex

including neurotransmission

TOK-1 Polyclonal Antibody, 20ul Mammalian Expression This protein acts as aBCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N terminal half shares moderate homology with regions of calmodulin and M calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a

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