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They have been shown to inhibit the expression of IFN-, IL-6, IL-1, and IL-2

doi: 10.3389/fimmu.2025.1722463 Received 10 October 2025 Revised 03 December 2025 Accepted 12 December 2025 Published 12 January 2026 Volume 16 - 2025 Edited by Gabriella dEttorre, Sapienza University of Rome, Italy Reviewed by Christina K

Modulation of A production As the enzyme BACE1 plays a crucial role in the production of A, a key factor in AD, inhibiting BACE1 activity represents a promising therapeutic strategy