Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma Contraction of the macrosatellite repeat

Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD)

The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases

Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization

High chemical compatibility with use of inert materials and glass/PTFE piston

Pim-1(Phospho Tyr309) Polyclonal Antibody, 100ul Plasma Contraction of the macrosatellite repeatThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes