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Figure 2 Further analysis of suicidal ideation or attempts at 3, 6, and 12 months revealed adjusted hazard ratios of 0.04 (95% CI: 0.020.08), 0.07 (95% CI: 0.040.13), and 0.12 (95% CI: 0.080.20), respectively, demonstrating a consistent reduction in risk over time in the tirzepatide group compared to the control group ( Table 2 )

Individuals with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia type 2 (MEN2) should discuss this with their clinician before considering any GLP-1based therapy, and should be alert to symptoms such as a neck lump, hoarseness, or difficulty swallowing

The patient also did not present with a history of melanoma

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