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There are several ongoing studies

The retinol dehydrogenases that have been shown to be involved in retinaldehyde and retinol interconversions are members of the short-chain dehydrogenase/reductase (SDR) superfamily of enzymes

However, the levels of other metabolites such as 5-Aminolevulinate, cysteate, putrescine, 4-Aminobutyraldehyde, kynurenine, serotonin, Formyl-5-hydroxykynurenamine, 5-Hydroxykynurenine, 2-Aminomuconate, xanthine, and 5-Aminolevulinate were significantly increased in LC patients ( Figure 3C , Supplementary Figure 3A )