NF Kappa B p65 Monoclonal Antibody(14H2), 50ul Shakers When overexpressed in cells is

When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner

Mutations in this gene are associated with xeroderma pigmentosum complementation group A

The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance

it is thought to play a role in nitric oxide and polyamine metabolism

NF Kappa B p65 Monoclonal Antibody(14H2), 50ul Shakers When overexpressed in cells isNF kappa B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF kappa B moves to the nucleus and activates transcription of specific genes. NF kappa B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF kappa B is NFKB1 complexed with the product of this gene, RELA. Four