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PubMed CrossRef Vidarsdottir S, de Leeuw van Weenen JE, Frlich M, et al

Anabolic resistance increases with age, meaning your muscles require a larger protein stimulus to achieve the same preservation response

Of particular significance, three large-scale meta-analyses examining the relationship between metformin and prostate cancer risk demonstrated that while metformin significantly improved the prognosis of prostate cancer patients, its use showed no significant association with prostate cancer incidence