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The analysis identified key structural features(such as topological indices) associated with drug efficacy, providing valuable insight for the design of more effective AD therapeutics (11)

According to Table 3 , a characteristic pro-inflammatory state can be observed in SZ patients, manifested by persistently elevated levels of pro-inflammatory cytokines such as IL-6, IL-1, and TNF- in both peripheral blood and CSF, accompanied by a relative deficiency of anti-inflammatory cytokines like IL-10 and TGF-