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Furthermore, vitamin D enhances mitochondrial function by improving oxidative phosphorylation efficiency, reducing electron leakage, and upregulating antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx)

Inclusion criteria consisted of newly diagnosed, pathologically confirmed epithelial ovarian cancer, an age of 18 years or older, the ability to provide informed consent, willingness to provide access to medical records, undergoing interval or primary debulking surgery at UPMC/HCC, completing a full course (six cycles) of platinum-based chemotherapy at UPMC/HCC and willingness to provide biospecimens for banking purposes