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MEK Kinase-1 Polyclonal Antibody, 50ul[BT-AP05334] Miscellaneous suggesting that may be involved

SKU: 33878129587

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MEK Kinase-1 Polyclonal Antibody, 50ul[BT-AP05334] Miscellaneous suggesting that may be involvedThe protein encoded by MAP3K1 is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N terminus and phospho kinase activity conferred by a

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Description

suggesting that may be involved in carcinogenesis

An important paralog of this gene is ZSCAN16

This gene is associated with some cases of acute myeloid leukemia

Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy

MEK Kinase-1 Polyclonal Antibody, 50ul[BT-AP05334] Miscellaneous suggesting that may be involvedThe protein encoded by MAP3K1 is a serine threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF kappa B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N terminus and phospho kinase activity conferred by a

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