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With normal amounts of folate and B12, the body is able to convert homocysteine into glutathione and SAMe (S-adenosylmethionine)

Notably, DRP-104 demonstrates the ability to counter T cell exhaustion and enhance the functionality of both CD4 + and CD8 + T cells [188]

Further, the author demonstrated that this damage was restricted to mitochondrial DNA instead of nuclear DNA, which might be because of limited mitochondrial repair pathways (Yanez et al