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J.ScalisiG.RothhammerV.et al (2019)

Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression

IGFBP-2 regulates the bioavailability of IGF-1 by binding to it, although the study did not record significant changes in their expression post-exposure to the peptide