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MIN6 and SK-N-MC cells were cultured in 100 mm dishes and exposed to an ethanolic extract of Protandim or ethanolic extracts of its components at concentrations indicated in Table 10 below for 24 hours

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Nat Struct Biol 8 : 10581063 Garcia-Echeverria C, Pearson MA, Marti A, Meyer T, Mestan J, Zimmermann J, Gao J, Brueggen J, Capraro HG, Cozens R, Evans DB, Fabbro D, Furet P, Porta DG, Liebetanz J, Martiny-Baron G, Ruetz S, Hofmann F (2004) In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase