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doi: 10.1016/j.reprotox.2017.07.020 36 BabakhanzadehENazariMGhasemifarSKhodadadianA

Losing weight too quickly can lead to muscle loss and other concerns

Until an approval decision is issued, CagriSema remains investigational in the U.S

Tirzepatide (Zepbound) - FDA Approved 2023: According to clinical trials cited by multiple sources including NBC News, tirzepatide (a GIP/GLP-1 dual agonist) showed approximately 21% to 22.5% mean weight loss on its highest dose after 72 weeks, compared to approximately 3% for placebo