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polysaccharide (PAP) significantly reduced LPS-induced ALI inflammation and inhibited M1 macrophage immune responses by activating the Rap1 signaling pathway [111]

Red Flags: Elevations in liver enzymes require dose adjustment or further investigation

Assessment of 8-hydroxy-guanosine (oh8G) as an indicator of oxidative DNA damage has displayed that ROS-induced DNA oxidation during the freezing procedures can be decreased after adding L-carnitine to the cryomedium (81)