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CD42c Polyclonal Antibody, 20ul Endonucleases & Exonucleases CDKL3 was identified as a

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CD42c Polyclonal Antibody, 20ul Endonucleases & Exonucleases CDKL3 was identified as aPlatelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb V IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane

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Description

CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion

as only a minority of individuals showed biased expression from the maternal allele

Biochemical and genetic data suggest a role as a tumor suppressor

which exists in both membrane-bound and secreted forms

CD42c Polyclonal Antibody, 20ul Endonucleases & Exonucleases CDKL3 was identified as aPlatelet glycoprotein Ib (GPIb) is a heterodimeric transmembrane protein consisting of a disulfide linked 140 kD alpha chain and 22 kD beta chain. It is part of the GPIb V IX system that constitutes the receptor for von Willebrand factor (VWF), and mediates platelet adhesion in the arterial circulation. GPIb alpha chain provides the VWF binding site, and GPIb beta contributes to surface expression of the receptor and participates in transmembrane

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