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The clinical trials supporting Saxenda's approval did not investigate this combination, meaning evidence on safety and efficacy remains limited

965 SLN124 normalizes hepcidin expression and reduces anemia in Hbb th3/+ mice

It is suggested that the differential modulation of MR co-factors is associated with the specific ability of finerenone to improve the expression of tenascin X (TNX), an MR target gene that plays a crucial role in fibrosis regulation (211)