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Specific alterations include reductions in Prevotella , Coprococcus , and Veillonellaceae , alongside overgrowth of Desulfovibrio (positively correlated with Autism spectrum disorder severity) (258), Sutterella , Ruminococcus , Clostridium , Megamonas , and Candida ( 259, 260), accompanied by an elevated Firmicutes/Bacteroidetes ratio (255)

This issue of inadequate energy delivery, coupled with the lack of standardisation in treatment parameters (such as wavelength, power, and energy density), and variations in individual anatomical structures and tissue optical properties, collectively contributes to inconsistent clinical research outcomes, limiting the maximisation of PBMT efficacy (8)

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